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Diltiazem was approved for medical use in the United States in 1982. [9] It is available as a generic medication. [9] In 2022, it was the 100th most commonly prescribed medication in the United States, with more than 6 million prescriptions. [13] [14] An extended release formulation is also available. [5] [6] [9]
Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1]
Calcium channel blocker toxicity is the taking of too much of the medications known as calcium channel blockers (CCBs), either by accident or on purpose. [3] This often causes a slow heart rate and low blood pressure. [1]
The weight loss drug Zepbound, generically known as tirzepatide, is also now an approved medication to treat obstructive sleep apnea, per a Food and Drug Administration Dec. 20 press release.
Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
The substances may act on the drug's capsule to speed up drug release, or they may stimulate the body's absorptive surfaces to increase the rate of drug uptake. Dose dumping is a disadvantage found in extended release dosage form. In general, drug companies try to avoid drugs with significant dose dumping effects. Such drugs are prone to ...
A 33-year-old man was charged Monday for allegedly setting on fire and killing a woman on a New York subway train in what authorities called a “brutal murder” and an example of “depraved ...
Jennifer Aniston does not abide by one popular health mantra. "No pain, no gain. That's not true at all," the actress, 55, tells PEOPLE in an exclusive interview. "You can actually have gain with ...