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The main cause of TB is Mycobacterium tuberculosis (MTB), a small, aerobic, nonmotile bacillus. [8] The high lipid content of this pathogen accounts for many of its unique clinical characteristics. [54] It divides every 16 to 20 hours, which is an extremely slow rate compared with other bacteria, which usually divide in less than an hour. [55]
Nationally, TB is on the rise, with 8,331 cases reported in 2022, a 5.9% increase over 2021, according to the CDC. It is unclear if 8,331 is just active cases or includes latent cases.
The medical history includes obtaining the symptoms of pulmonary TB: productive, prolonged cough of three or more weeks, chest pain, and hemoptysis.Systemic symptoms include low grade remittent fever, chills, night sweats, appetite loss, weight loss, easy fatiguability, and production of sputum that starts out mucoid but changes to purulent. [1]
Miliary tuberculosis is a form of tuberculosis that is characterized by a wide dissemination into the human body and by the tiny size of the lesions (1–5 mm). Its name comes from a distinctive pattern seen on a chest radiograph of many tiny spots distributed throughout the lung fields with the appearance similar to millet seeds—thus the term "miliary" tuberculosis.
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
Intermittent fever is a type or pattern of fever in which there is an interval where temperature is elevated for several hours followed by an interval when temperature drops back to normal. [1] This type of fever usually occurs during the course of an infectious disease . [ 2 ]
When collecting pericardial fluid is not possible, the Tygerberg scoring system helps the clinician to decide whether pericarditis is due to tuberculosis or another cause. [5] In tuberculosis-endemic regions, ≥6 points is highly predictive of tuberculous pericarditis: [5] Fever = 2 points; Night sweats = 1 point; Loss of body mass = 1 points
“Norovirus is the leading cause of vomiting and diarrhea from acute gastroenteritis in the U.S., responsible for 58% of foodborne illnesses and about 2,500 outbreaks annually,” Justman says.