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Additionally, chemical burns can be caused by biological toxins (such as anthrax toxin) and by some types of cytotoxic chemical weapons, e.g., vesicants such as mustard gas and Lewisite, or urticants such as phosgene oxime. Chemical burns may: need no source of heat; occur immediately on contact; not be immediately evident or noticeable; be ...
Lewisite was replaced by the mustard gas variant HT (a 60:40 mixture of sulfur mustard and O-Mustard), and was declared obsolete in the 1950s. Lewisite poisoning can be treated effectively with British anti-lewisite (dimercaprol). Most stockpiles of lewisite were neutralised with bleach and dumped into the Gulf of Mexico. [25]
All blister agents currently known are denser than air, and are readily absorbed through the eyes, lungs, and skin. Effects of the two mustard agents are typically delayed: exposure to vapors becomes evident in 4 to 6 hours, and skin exposure in 2 to 48 hours. The effects of Lewisite are immediate.
The carcinogenic and mutagenic effects of exposure to mustard gas increase the risk of developing cancer later in life. [3] In a study of patients 25 years after wartime exposure to chemical weaponry, c-DNA microarray profiling indicated that 122 genes were significantly mutated in the lungs and airways of mustard gas victims.
Depending on the type and amount of irritant gas inhaled, victims can experience symptoms ranging from minor respiratory discomfort to acute airway and lung injury and even death. A common response cascade to a variety of irritant gases includes inflammation , edema and epithelial sloughing , which if left untreated can result in scar formation ...
This chemical is a form of nitrogen mustard gas and a powerful vesicant. Historically, some uses of mechlorethamine have included lymphoid malignancies such as Hodgkin's disease, lymphosarcoma, chronic myelocytic leukemia, polycythemia vera, and bronchogenic carcinoma [ 7 ] Mechlorethamine is often administered intravenously, [ 8 ] but when ...
Effects of nitrogen mustard exposure can be long-term or permanent; it is also a known carcinogen, reprotoxin, and developmental toxin after chronic and acute exposure, causing skin cancer and airway cancers in particular. Blindness from an acute exposure is usually temporary, resolving in days to months depending on severity.
Abnormal lung sounds (wet or gurgling sounds when breathing) [2] Chest pain, tightness or burning sensation [4] Chronic: Persistent cough [4] Shortness of breath [2] Increased susceptibility to respiratory illness [4] Symptoms of chronic chemical pneumonitis may or may not be present, and can take months or years to develop to the point of ...