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Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the ...
The metanephridia, together with the vascular filtration site and coelom, are functionally identical to the ancestral primitive kidneys of vertebrates. [14] The main structural and functional element of the kidney is the nephron. [15] Between animals, the kidneys can differ in the number of nephrons and in their organisation. [16]
Centrifugal filtration is carried out by rapidly rotating the substance to be filtered. The more dense material is separated from the less dense matter by the horizontal rotation. [4] Gravity filtration is the process of pouring the mixture from a higher location to a lower one. It is frequently accomplished via simple filtration, which ...
By convention, outward force is defined as positive, and inward force is defined as negative. The solution to the equation is known as the net filtration or net fluid movement (J v). If positive, fluid will tend to leave the capillary (filtration). If negative, fluid will tend to enter the capillary (absorption). This equation has a number of ...
The human urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, bladder, and the urethra. The purpose of the urinary system is to eliminate waste from the body, regulate blood volume and blood pressure, control levels of electrolytes and metabolites , and regulate blood pH .
The processes of blood plasma filtration, tubular reabsorption and tubular secretion occur in the kidneys, and urine formation is a result of these processes. [8] The kidneys produce renin [32] and erythropoietin [33] hormones, and are involved in the conversion of vitamin D to its active form. [34]
The filtration fraction is the amount of plasma that is actually filtered through the kidney. This can be defined using the equation: FF= GFR / RPF FF is the filtration fraction; GFR is the glomerular filtration rate; RPF is the renal plasma flow; Normal human FF is 20%.
Glomerular filtration will only remove those drugs or metabolites that are not bound to proteins present in blood plasma (free fraction) and many other types of drugs (such as the organic acids) are actively secreted. In the proximal and distal convoluted tubules, non-ionised acids and weak bases are reabsorbed both actively and passively. Weak ...