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Hemorrhoids (or haemorrhoids), also known as piles, are vascular structures in the anal canal. [ 7 ] [ 8 ] In their normal state, they are cushions that help with stool control. [ 2 ] They become a disease when swollen or inflamed ; the unqualified term hemorrhoid is often used to refer to the disease. [ 8 ]
Tribenoside (Glyvenol) is a vasoprotective drug used to treat hemorrhoids. [1] It has mild anti-inflammatory, analgesic, and wound healing properties. [2] Tribenoside stimulates laminin α5 production and laminin-332 deposition to help repair the basement membrane during the wound healing process. [3] It is a mixture of the α- and β-anomers ...
Medications typically include octreotide or, if not available, vasopressin and nitroglycerin to reduce portal venous pressures. [13] Terlipressin appears to be more effective than octreotide, but it is not available in many areas of the world. [16] [30] It is the only medication that has been shown to reduce mortality in acute variceal bleeding ...
Certain medications, such as calcium channel blockers or proton pump inhibitors, can exacerbate anorectal symptoms by causing diarrhea or constipation, or they can exacerbate bleeding (e.g., Coumadin, nonsteroidal anti-inflammatory drugs). A history of hemorrhoidectomy, fissure surgery, fistula surgery, polypectomy, or colectomy may be relevant.
Anorectal disorders include conditions involving the anorectal junction [1] as seen in the image. They are painful but common conditions like hemorrhoids, tears, fistulas, or abscesses that affect the anal region. [2] [3] Most people experience some form of anorectal disorder during their lifetime. [4]
Perianal hematoma are caused by the rupture of a small vein that drains blood from the anus. [4] This rupture may be the result of forceful or strained bowel movement, anal sex or caused by heavy lifting, coughing or straining.
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