Search results
Results from the WOW.Com Content Network
Immortalised cell lines are widely used as a simple model for more complex biological systems – for example, for the analysis of the biochemistry and cell biology of mammalian (including human) cells. [2] The main advantage of using an immortal cell line for research is its immortality; the cells can be grown indefinitely in culture.
HeLa (/ ˈ h iː l ɑː /) is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. [1] [2] HeLa cells are durable and prolific, allowing for extensive applications in scientific study.
Human cells are considered to be a more predictive model and a replacement for other cellular models that serve as proxies, including animal cells, immortalized cell lines, and cadaveric cells. [ 3 ] FCDI offers several terminally differentiated cell types as catalog products: iCell® Cardiomyocytes, iCell Neurons, iCell Endothelial Cells, and ...
Astrocytes (green) in the context of neurons (red) in a mouse cortex cell culture 23-week-old fetal brain culture human astrocyte Astrocytes (red-yellow) among neurons (green) in the living cerebral cortex. Astrocytes are a sub-type of glial cells in the central nervous system. They are also known as astrocytic glial cells.
Among the most commonly used cell lines are HeLa and Jurkat, both of which are immortalized cancer cell lines. [4] These cells have been and still are widely used in biological research such as creation of the polio vaccine, [5] sex hormone steroid research, [6] and cell metabolism. [7] Embryonic stem cells and germ cells have also been ...
Henrietta Lacks (born Loretta Pleasant; August 1, 1920 – October 4, 1951) [2] was an African-American woman [5] whose cancer cells are the source of the HeLa cell line, the first immortalized human cell line [B] and one of the most important cell lines in medical research. An immortalized cell line reproduces indefinitely under specific ...
OPCs may retain the ability to differentiate into astrocytes into adulthood. [42] [43] Using NG2-Cre mice, it was shown that OPCs in the prenatal and perinatal grey matter of the ventral forebrain and spinal cord generate protoplasmic type II astrocytes in addition to oligodendrocytes. However, contrary to the prediction from optic nerve ...
Non-human primates are useful as they have a more similar aging pattern to humans compared to rodent models. [60] During non-human primate aging, they can display neuropathy, cognitive changes, and amyloid-β deposits, similar to that of Alzheimer's disease. [60]