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A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel, [1] which are a type of calcium channel regulated by changes in membrane potential. Some calcium channels are regulated by the binding of a ligand.
P-type calcium channel ("Purkinje") /Q-type calcium channel: HVA (high voltage activated) Ca v 2.1 : α 2 δ, β, possibly γ: Purkinje neurons in the cerebellum / Cerebellar granule cells: N-type calcium channel ("Neural"/"Non-L") HVA (high voltage activated) Ca v 2.2 : α 2 δ/β 1, β 3, β 4, possibly γ: Throughout the brain and peripheral ...
Ca v 2.1, also called the P/Q voltage-dependent calcium channel, is a calcium channel found mainly in the brain. [5] Specifically, it is found on the presynaptic terminals of neurons in the brain and cerebellum. [5] Ca v 2.1 plays an important role in controlling the release of neurotransmitters between neurons. [5]
N-type calcium channels are categorized as high threshold-activated channels and seen in the Cav2 gene family. The structure of the N-type calcium channel is very similar to other voltage-dependent channels. The most important part of the channel is the actual pore that is formed by the α1B subunit.
An L-type calcium channel with its subunits labeled along with some drugs known to inhibit the channel. The L-type calcium channel (also known as the dihydropyridine channel, or DHP channel) is part of the high-voltage activated family of voltage-dependent calcium channel. [2] "L" stands for long-lasting referring to the length of activation ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human The R-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α 1 subunit forms the pore through which calcium enters the cell and determines most of the channel's properties. This α 1 subunit ...
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Calcium channel, voltage-dependent, L type, alpha 1D subunit (also known as Ca v 1.3) is a protein that in humans is encoded by the CACNA1D gene. [5] Ca v 1.3 channels belong to the Ca v 1 family, which form L-type calcium currents and are sensitive to selective inhibition by dihydropyridines (DHP).