Search results
Results from the WOW.Com Content Network
The secreted toxin attaches to the surface of the host mucosa cell by binding to GM1 gangliosides. GM1 consists of a sialic acid-containing oligosaccharide covalently attached to a ceramide lipid. The A1 subunit of this toxin will gain entry to intestinal epithelial cells with the assistance of the B subunit via the GM1 ganglioside receptor.
A ganglioside is a molecule composed of a glycosphingolipid ... Structures of GM1, GM2, GM3. One NANA ("M") GM1; GM2; GM3; Two NANAs ("D") GD1a; GD1b; GD2; GD3; Three ...
This enzyme catalyses the formation of the gangliosides (i.e. sialic-acid-containing glycosphingolipids) GM2, GD2 and SM2 from GM3, GD3 and SM3, respectively. References [ edit ]
The GM1 gangliosidoses, usually shortened to GM1, are gangliosidoses caused by mutation in the GLB1 gene resulting in a deficiency of beta-galactosidase.The deficiency causes abnormal storage of acidic lipid materials in cells of the central and peripheral nervous systems, but particularly in the nerve cells, resulting in progressive neurodegeneration.
The cozy slippers that are 'just like UGGs but at a great price' are down to $24. AOL. ... USA TODAY. Boar's Head, cucumbers, frozen waffles, McDonald's: The biggest food recalls of 2024.
Levels of anti-GM1 antibodies are especially elevated in patients with prodromal diarrhea. [7] Titers to GM1 in other diseases (rheumatoid arthritis, primary Sjögren's syndrome and systemic lupus erythematosus) was also elevated. [8] Additionally highly significant association was found with rheumatoid arthritis and peripheral neuropathies. [9]
Citi analysts forecast 19% earnings growth for the healthcare sector in 2025, up from 4% this year. The analysts point to the stocks' right-sized valuations and a potential improvement in ...
Despite the better outlook on price increases, “consumers overwhelmingly selected higher prices as their top concern and lower prices as their top wish for the new year,” the Conference Board ...