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On Friday, trial data presented at the American Society of Clinical Oncology meeting in Chicago showed that Trodelvy improved survival by just 1.3 months more than chemotherapy for patients with ...
Apolo designs and implements clinical trials to test novel agents for the treatment of urologic cancers. Her research focuses on developing targeted therapies for bladder cancer and rare genitourinary tumors, including immunotherapies, angiogenesis inhibitors, and agents that target MET, and in identifying molecular alterations that will serve as targets for individualized treatment strategies.
The safety and effectiveness of nadofaragene firadenovec was evaluated in a multicenter clinical study (Study CS-003 (NCT02773849)) that included 157 participants with high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer, 98 of whom had BCG-unresponsive carcinoma in situ with or without papillary tumors and could be evaluated for response.
Clinical trial number NCT0302285 for "QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer" at ClinicalTrials.gov
Bladder cancer is much more common in men than women; around 1.1% of men and 0.27% of women develop bladder cancer. [2] This makes bladder cancer the sixth most common cancer in men, and the seventeenth in women. [57] When women are diagnosed with bladder cancer, they tend to have more advanced disease and consequently a poorer prognosis. [57]
Clinical trial number NCT02387996 for "A Study of Nivolumab in Participants With Metastatic or Unresectable Bladder Cancer" at ClinicalTrials.gov; Clinical trial number NCT02060188 for "An Investigational Immuno-therapy Study of Nivolumab, and Nivolumab in Combination With Other Anti-cancer Drugs, in Colon Cancer That Has Come Back or Has ...
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