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There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity. Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g., heparin, lithium).
Samoyeds can be affected by basement membrane disease of the kidneys. It is inherited through the X chromosome and is therefore more severe in affected male dogs. Findings in male dogs include the presence of protein and glucose in the urine and the inability to concentrate urine, and progression to kidney failure by the age of 9 months and death by 16 months. [3]
The dog medication Librela is likely sickening and killing dogs, the FDA warned. Ermolaev Alexandr – stock.adobe.com More than 3,600 cases of Librela harming dogs have been reported to the FDA.
It can result in chronic kidney failure, hypoalbuminemia, which can cause ascites and peripheral edema, and nephrotic syndrome, which can cause hypertension or hypercoagulability. [156] Familial renal disease is an uncommon cause of kidney failure in young dogs. Most causes are breed-related (familial) and some are inherited.
This Australian Cattle Dog's obesity poses a health risk for the dog. Obesity is an increasingly common problem in dogs in Western countries. As with humans, obesity can cause numerous health problems in dogs (although dogs are much less susceptible to the common cardiac and arterial consequences of obesity than humans are).
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Deracoxib is a coxib class nonsteroidal anti-inflammatory drug (NSAID). [3] Like other NSAIDs, its effects are caused by inhibition of cyclooxygenase (COX) enzymes. [7] At the doses used to treat dogs, deracoxib causes greater inhibition of COX-2 than of COX-1, [3] but at doses twice those recommended for use in dogs, deracoxib significantly inhibits COX-1 as well.
Animal euthanasia (euthanasia from Greek: εὐθανασία; "good death") is the act of killing an animal humanely, most commonly with injectable drugs.Reasons for euthanasia include incurable (and especially painful) conditions or diseases, [1] lack of resources to continue supporting the animal, or laboratory test procedures.