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Pseudoephedrine, the decongestant found in Sudafed, is highly effective in helping people with stuffy noses breathe more easily, said Dr. Maryann Amirshahi, a medical toxicologist and a professor ...
The U.S. Food and Drug Administration (FDA) announced that it plans to ban products containing phenylephrine, an ingredient found in many over-the-counter (OTC) oral cold and flu medications.
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Do over-the-counter decongestants like Sudafed PE work? Doctors have said oral phenylephrine is ineffective to relieve nasal congestion. An FDA panel will reevaluate the evidence.
A majority of an oral dose of pseudoephedrine is excreted unchanged in urine within 24 hours of administration. [11] This has been found to range from 43 to 96%. [ 1 ] [ 11 ] [ 2 ] The amount excreted unchanged is dependent on urinary pH similarly to the drug's half-life, as a longer half-life and duration in the body allows more time for the ...
Until 2006, NyQuil Cold/Flu Multisymptom Relief and NyQuil Sinus contained pseudoephedrine (30 mg/15 mL), a nasal decongestant that also formed the active ingredient in Sudafed. Following the passage of the Combat Methamphetamine Epidemic Act in 2006, in the United States all pseudoephedrine-containing medications must be kept behind a pharmacy ...
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