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Due to the anti-parallel nature of DNA, this means the 3' end of the template strand is upstream of the gene and the 5' end is downstream. Some genes on the same DNA molecule may be transcribed in opposite directions. This means the upstream and downstream areas of the molecule may change depending on which gene is used as the reference.
Downstream may refer to: Downstream (hydrology) , the direction towards the mouth of a stream, i.e. the direction the current flows Downstream (bioprocess) , when a cell mass from an upstream process (isolated, grown and harvested) is further processed to meet purity and quality requirements
The extracellular type II and type I kinase receptors binding to the TGF-β ligands. Transforming growth factor-β (TGF-β) is a superfamily of cytokines that play a significant upstream role in regulating of morphogenesis, homeostasis, cell proliferation, and differentiation. [2]
Computer science [ edit ] Upstream and Downstream , the notional directions which lie "towards" and "away from" the author of a piece of software, relative to the speaker
Downstream processing and analytical bioseparation both refer to the separation or purification of biological products, but at different scales of operation and for different purposes. Downstream processing implies manufacture of a purified product fit for a specific use, generally in marketable quantities, while analytical bioseparation refers ...
As water flows downstream, streams and rivers most often gain water volume, so at base flow (i.e., no storm input), smaller headwater streams have very low discharge, while larger rivers have much higher discharge. The "flow regime" of a river or stream includes the general patterns of discharge over annual or decadal time scales, and may ...
These terms are defined from the perspective of looking downstream, that is, facing the direction the water current of the main stem is going. In a navigational context, if one were floating on a raft or other vessel in the main stream, this would be the side the tributary enters from as one floats past; alternately, if one were floating down ...
This definition, from geographer Andrew Johnston of the Smithsonian Institution, is also used by the National Geographic Society when pinpointing the source of rivers such as the Amazon or Nile. A definition given by the state of Montana agrees, stating that a river source is never a confluence but is "in a location that is the farthest, along ...
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