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Axial spondyloarthritis (also often referred to as axSpA) is a chronic, immune-mediated disease predominantly affecting the axial skeleton (sacroiliac joints and spine). [1] The term itself is an umbrella term characterizing a diverse disease family united by shared clinical and genetic features, such as the involvement of the axial skeleton. [ 2 ]
When peripheral arthritis coexists with axial illness, conventional DMARDs such methotrexate, [37] sulfasalazine, [38] or leflunomide may be useful in treating peripheral spondyloarthritis. [39] These drugs are typically ineffective in treating axial symptoms of spondyloarthritis. [40]
Ankylosing spondylitis is a member of the more broadly defined disease axial spondyloarthritis. [23] [24] Axial spondyloarthritis can be divided into two categories: radiographic axial spondyloarthritis (which is a synonym for ankylosing spondylitis) and non-radiographic axial spondyloarthritis (which include less severe forms and early stages ...
About 50 percent of people can manage the symptoms of axSpA with over-the-counter pain relievers, says Dr. Reveille, whereas the other half, who have more advanced forms of axial spondyloarthritis ...
“The symptoms include back pain, but primarily stiffness,” says Alexis Ogdie, MD, a professor of rheumatology at Penn Medicine in Philadelphia. ... In the case of axial spondyloarthritis ...
When symptoms flare up, use these tips to calm and find solace. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ways to reach us. Mail ...
It is a feature of spondyloarthropathies, such as axial spondyloarthritis (including ankylosing spondylitis), psoriatic arthritis, reactive arthritis or arthritis related to inflammatory bowel diseases, including ulcerative colitis or Crohn's disease. It is also the most common presentation of arthritis from brucellosis.
If you are one of the approximately 1.5 percent of Americans who have been diagnosed with axial spondyloarthritis (axSpA)—a chronic inflammatory rheumatic disease that can cause pain, stiffness ...