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The reaction is informally termed Asian flush due to its frequent occurrence in East Asians, with approximately 30 to 50% of Chinese, Japanese, and Koreans showing characteristic physiological responses to drinking alcohol that includes facial flushing, nausea, headaches and a fast heart rate.
[34] [35] [36] On the other hand, the more uncommon alcohol allergy is an immune system reaction to alcohol (specifically ethanol) that causes symptoms such as rashes, difficulty breathing, and anaphylaxis in severe cases. [37] [38] Nausea is a symptom common to both alcohol intolerance and alcohol allergy. [35]
The alcohol flush reaction is also primarily “due to inherited variations in genes of certain enzymes” – found among people of East Asian ancestry – that cause them “to metabolise ...
Alcohol flush reaction as a result of the accumulation of acetaldehyde, the first metabolite of alcohol Main article: Pharmacology of ethanol After being ingested, the ethanol in alcoholic beverages is first converted to acetaldehyde by the enzyme alcohol dehydrogenase and then to acetic acid by oxidation and egestion process.
Acetaldehyde is also linked to some of the unpleasant symptoms of alcohol intoxication, such as headaches, flushing, hives and nausea, according to Lee. This type of genetic test may provide an ...
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Alcohol flush reaction is a condition in which an individual's face or body experiences flushes (appears red) or blotches as a result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol. It is best known as a condition that is experienced by people of Asian descent.
Such atypical alcohol dehydrogenase levels are less frequent in alcoholics than in non-alcoholics. [5] Furthermore, among alcoholics, the carriers of this atypical enzyme consume lower ethanol doses, compared to the individuals without the allele. [citation needed] An estimated one out of twenty people have an alcohol flush reaction. It is not ...