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Coxsackie B infections usually do not cause serious disease, although for newborns in the first 1–2 weeks of life, Coxsackie B infections can easily be fatal. [2] The pancreas is a frequent target, which can cause pancreatitis. [2] Coxsackie B3 (CB3) infections are the most common enterovirus cause of myocarditis and sudden cardiac death. [8]
Bornholm disease, also known as epidemic pleurodynia, [1] is a condition characterized by myositis of the abdomen or chest caused by the Coxsackie B virus or other viruses. [2] The myositis manifests as an intermittent stabbing pain in the musculature that is seen primarily in children and young adults. [3]
Coxsackieviruses are divided into group A and group B viruses based on early observations of their pathogenicity in neonatal mice. [1] Group A coxsackieviruses were noted to cause a flaccid paralysis (which was caused by generalized myositis) while group B coxsackieviruses were noted to cause a spastic paralysis (due to focal muscle injury and degeneration of neuronal tissue).
Coxsackievirus A16 is the most common cause, and enterovirus 71 is the second-most common cause. [6] Other strains of coxsackievirus and enterovirus can also be responsible. [6] [12] Some people may carry and pass on the virus despite having no symptoms of disease. [10] Other animals are not involved. [8] Diagnosis can often be made based on ...
There are several viral infections that can affect the throat and uvula, many of which also cause cold symptoms (runny nose, cough, laryngitis). “Some viruses, like coxsackie (hand, foot, and ...
A diagnosis can be made from clinical signs and symptoms, and treatment consists of minimizing the discomfort of symptoms. [5] It can be differentiated from herpetic gingivostomatitis by the positioning of vesicles - in herpangina, they are typically found on the posterior oropharynx, as compared to gingivostomatitis where they are typically found on the anterior oropharynx and the mouth.
Coxsackievirus group A is known for causing hand-foot-and-mouth diseases while Group B, which contains six serotypes, can cause a varying range of symptoms like gastrointestinal distress myocarditis. Coxsackievirus B4 has a cell tropism for natural killer cells and pancreatic islet cells.
Enterovirus B includes coxsackievirus B1,2,3,4,5,6; coxsackievirus A9; echovirus 1–33 and enterovirus B69–113. [11] Coxsackie B viruses are found worldwide and can cause myocarditis (inflammation of the heart); pericarditis (inflammation of the sac surrounding the heart); meningitis (inflammation of the membranes that line the brain and ...