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Osteogenesis imperfecta (IPA: / ˌ ɒ s t i oʊ ˈ dʒ ɛ n ə s ɪ s ˌ ɪ m p ɜːr ˈ f ɛ k t ə /; [4] OI), colloquially known as brittle bone disease, is a group of genetic disorders that all result in bones that break easily. [1]: 85 [9] The range of symptoms—on the skeleton as well as on the body's other organs—may be mild to severe.
The bone edema in arthritis mutilans can be treated with TNF inhibitors in the short term: a 2007 study found that the bone edema associated with psoriatic arthritis (of which arthritis mutilans is a subtype) responded to TNF inhibitors with "dramatic" improvement, but the study was not determinative of whether TNF inhibitors would prevent new ...
As a child, she sometimes intentionally broke her bones because after a break was the only time that her neglectful and abusive father ever showed her affection. As an adult, she dies from falling down a flight of stairs. Jodi Picoult's character Willow O'Keefe from the 2009 book Handle with Care is born with type III. Her mother files a ...
Humans have been drinking wine for over 6,000 years.Nearly every part of the world has their own winemaking traditions and different varietals of grapes, fermentation techniques, and climates that ...
“Some studies suggest that moderate wine consumption, particularly red wine, may be associated with a reduced risk of cognitive decline and certain neurodegenerative diseases like Alzheimer's ...
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Running long distance can cause pain to the knee joint, as it is a high-impact exercise. [2] The location and severity of knee pain may vary, depending on the cause of the problem. Signs and symptoms that sometimes accompany knee pain include: [1] Swelling and stiffness; Redness and warmth to the touch; Weakness or instability; Popping or ...
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).