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  2. Myasthenia gravis - Wikipedia

    en.wikipedia.org/wiki/Myasthenia_gravis

    Generalized MG has muscle weakness with a variable combination of the bulbar, axial, or limb and respiratory muscles. [ 54 ] Patients can also be sub-grouped by the age of onset: juvenile-onset MG (onset age ≤ 18 years of age), early-onset MG (EOMG; 19–50 years of age), late-onset MG (LOMG; onset > 50 years of age), and very late-onset ...

  3. Calpainopathy - Wikipedia

    en.wikipedia.org/wiki/Calpainopathy

    Age of onset is highly variable, although symptoms usually appear between 8 and 15 years of age. [3] Patients usually lose the ability to ambulate 10 – 20 years after symptoms appear. [ 3 ] Milder forms present with symptoms other than weakness, such as muscle aches, cramps, or exercise intolerance, and people in this group can retain ...

  4. Muscle weakness - Wikipedia

    en.wikipedia.org/wiki/Muscle_weakness

    Its causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. Muscle weakness can also ...

  5. Sporadic late-onset nemaline myopathy - Wikipedia

    en.wikipedia.org/wiki/Sporadic_late-onset...

    Sporadic late-onset nemaline myopathy, or SLONM, is a very rare disease, one of the nemaline myopathies, causing loss of muscle bulk and weakness in the legs but sparing the cranial nerves, and beginning its clinical course after age 40. [1]

  6. Muscular dystrophy - Wikipedia

    en.wikipedia.org/wiki/Muscular_Dystrophy

    Generalised weakness Symptoms include general muscle weakness and possible joint deformities. Disease progresses slowly, and lifespan is shortened. Congenital muscular dystrophy includes several disorders with a range of symptoms. Muscle degeneration may be mild or severe.

  7. Guillain–Barré syndrome - Wikipedia

    en.wikipedia.org/wiki/Guillain–Barré_syndrome

    Guillain–Barré syndrome (also called "GBS") is a rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. [3] Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body. [3]

  8. Glycogen storage disease type V - Wikipedia

    en.wikipedia.org/wiki/Glycogen_storage_disease...

    Between 33-51.4% develop fixed muscle weakness, typically of the trunk and upper body, with the onset of muscle weakness usually occurring later in life (40+ years of age). [25] [24] Younger people may display unusual symptoms, such as difficulty in chewing, swallowing or utilizing normal oral motor functions. [26]

  9. Myotonic dystrophy - Wikipedia

    en.wikipedia.org/wiki/Myotonic_dystrophy

    DM causes muscle weakness, early onset of cataracts, and myotonia, which is delayed relaxation of muscles after contraction. [5] Cataracts can be either a cortical cataract with a blue dot appearance, or a posterior subcapsular cataract. [6] Other organs affected include the heart, lungs, gastrointestinal tract, skin, and brain. [5]