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  2. Prednisone - Wikipedia

    en.wikipedia.org/wiki/Prednisone

    Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36] [37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone. [38]

  3. Steroid-induced osteoporosis - Wikipedia

    en.wikipedia.org/wiki/Steroid-induced_osteoporosis

    The synthetic glucocorticoid prescription drug prednisone is a main candidate after prolonged intake. Bisphosphonates are beneficial in reducing the risk of vertebral fractures. [ 1 ] Some professional guidelines recommend prophylactic calcium and vitamin D supplementation in patients who take the equivalent of more than 30 mg hydrocortisone (7 ...

  4. Corticosteroid-induced lipodystrophy - Wikipedia

    en.wikipedia.org/wiki/Corticosteroid-induced_l...

    In a prospective study, the cumulative incidence of CIL with high-dose prednisone therapy was found to be 61% after 3 months, 65% after 6 months, 68% after 9 months, and 69% after 12 months. [1] One study found that even a very low dosage of prednisone of 5 mg/day was associated with symptoms of "Cushing's syndrome". [ 1 ]

  5. Management of ulcerative colitis - Wikipedia

    en.wikipedia.org/wiki/Management_of_ulcerative...

    Patients on high dose sulfasalazine require folic supplementation (1 mg/day) because it inhibits folate absorption. If oral Mesalazine is still not working, prednisone is often given, starting at 40–60 mg/day. Prednisone often takes effect within 10–14 days. The dose should then be tapered by about 5 mg/week until it can be stopped altogether.

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  7. Steroid-induced skin atrophy - Wikipedia

    en.wikipedia.org/wiki/Steroid-induced_skin_atrophy

    In people with psoriasis using topical steroids it occurs in up to 5% of people after a year of use. [5] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8] Skin atrophy can occur with both prescription and over the counter steroids creams. [9]

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  9. How much should you have in your 401(k)? Here's how your ...

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    For example, if you earn $80,000 annually, you should target about $240,000 in savings by age 40 and $480,000 by age 50. How much do most Americans retire with?

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