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Hypoxia can be due to external causes, when the breathing gas is hypoxic, or internal causes, such as reduced effectiveness of gas transfer in the lungs, reduced capacity of the blood to carry oxygen, compromised general or local perfusion, or inability of the affected tissues to extract oxygen from, or metabolically process, an adequate supply ...
Where the user must carry the supplementary oxygen supply, and also perform significant work over a fairly long period, as in mountaineering and rescue work, the efficiency of oxygen use and the reliability of the breathing apparatus are more important, and there is a trade-off of these characteristics with the weight that must be carried.
Finger tip carboxyhemoglobin saturation monitor.. A CO-oximeter is a device that measures the oxygen carrying state of hemoglobin in a blood specimen, including oxygen-carrying hemoglobin (O2Hb), non-oxygen-carrying but normal hemoglobin (HHb) (formerly, but incorrectly, referred to as 'reduced' hemoglobin), as well as the dyshemoglobins such as carboxyhemoglobin (COHb) and methemoglobin (MetHb).
Open-circuit oxygen apparatus was trialled on the 1922 and 1924 British Everest expeditions; the bottled oxygen taken by the 1921 expedition was not used. The carrying frame for open circuit oxygen designed by George Finch and used in 1922 and 1924 with four cylinders of oxygen weighed 32 lb (14.5 kg).
An open circuit SCBA typically has three main components: a high-pressure gas storage cylinder, (e.g., 2,216 to 5,500 psi (15,280 to 37,920 kPa), about 150 to 374 atmospheres), a pressure regulator, and a respiratory interface, which may be a mouthpiece, half mask or full-face mask, assembled and mounted on a framed carrying harness.
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