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Naloxone is useful in treating both acute opioid overdose and respiratory or mental depression due to opioids. [13] Whether it is useful in those in cardiac arrest due to an opioid overdose is unclear. [21] It is included as a part of emergency overdose response kits distributed to heroin and other opioid drug users, and to emergency responders.
Nalmefene. Nalmefene, sold under the brand name Revex among others, is a medication that is used in the treatment of opioid overdose and alcohol dependence. [2][3] Nalmefene belongs to the class of opioid antagonists and can be taken by mouth, administered by injection, or delivered through nasal administration. [8]
A second dose may be given if needed, similar to injectable epinephrine, the agency said. Neffy uses the same spray device as Narcan, the naloxone nasal spray for opioid overdose, according to a ...
Since the effects of epinephrine last up to 30 minutes, experts note that most of these side effects will subside during that time. The nasal spray will officially hit the market in eight weeks.
Severe allergic reactions: A nasal spray to treat severe allergic reactions could become the first non-injection alternative to fast-acting treatments like EpiPen. The FDA recently declined to ...
Intranasal drug delivery. Intranasal drug delivery occurs when particles are inhaled into the nasal cavity and transported directly into the nervous system. Though pharmaceuticals can be injected into the nose, some concerns include injuries, infection, and safe disposal. Studies demonstrate improved patient compliance with inhalation.
Nasal administration, popularly known as snorting, is a route of administration in which drugs are insufflated through the nose. It can be a form of either topical administration or systemic administration, as the drugs thus locally delivered can go on to have either purely local or systemic effects. Nasal sprays are locally acting drugs such ...
March 29, 2023 at 2:15 PM. The U.S. Food and Drug Administration on Wednesday approved selling the leading version of naloxone without a prescription, setting the overdose-reversing drug on course ...