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The hepatitis C virus (HCV) [3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma , abbreviated HCC) and lymphomas in humans.
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; [2] it is a type of viral hepatitis. [6] During the initial infection period, people often have mild or no symptoms. [1] Early symptoms can include fever, dark urine, abdominal pain, and yellow tinged skin. [1]
“Hepatitis C is a blood-borne virus,” says Dr. Dieterich. “It is transmitted through the blood, so IV drug use is a major driver of the virus, especially now due to the heroin epidemic.
The GB virus C is a virus that is probably spread by blood and sexual contact. [18] It was initially identified as Hepatitis G virus. [19] There is very little evidence that this virus causes hepatitis, as it does not appear to replicate primarily in the liver. [20] It is now classified as GB virus C. [21]
Hepatitis C virus (HCV), which is the causative agent of hepatitis C in humans, and a member of the species Hepacivirus C, was discovered in 1989. [5] Seven genotypes (1–7) and eighty-six subtypes (1a, 1b etc.) of hepatitis C virus have been named.
Hepatitis C virus (HCV) genotypes refer to the genetic variations that occurs in the hepatitis C virus. Hepatitis C is a contagious disease that primarily affects the liver, causing severe damage as the disease progresses. [1] It is caused by the Hepatitis C virus, a small, enveloped RNA virus.
The increase in intracellular reactive oxygen species is about 10,000-fold with chronic hepatitis B virus infection and 100,000-fold following hepatitis C virus infection. [25] This increase in reactive oxygen species causes inflammation [ 25 ] and more than 20 types of DNA damage. [ 26 ]
The orthohepadnaviruses have been divided into four distinct species, with HBV (human hepatitis B virus), WHV (woodchuck hepatitis virus), GSHV (ground squirrel hepatitis virus ), and WMHBV (woolly monkey hepatitis B virus) as the prototypes, based on the host range from a limited number of studies. From the result of molecular studies about ...
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