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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone - Wikipedia ... Spironolactone

  3. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    The pharmacodynamics of spironolactone, an antimineralocorticoid and antiandrogen medication, concern its mechanisms of action, including its biological targets and activities, as well as its physiological effects. The pharmacodynamics of spironolactone are characterized by high antimineralocorticoid activity, moderate antiandrogenic activity ...

  4. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    Legal status. In Wikidata. A mineralocorticoid receptor antagonist (MRA or MCRA) [1] or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors. This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure.

  5. The most popular pill to treat women's acne is a blood ... - AOL

    www.aol.com/news/most-popular-pill-treat-womens...

    The report, conducted on behalf of NBC News, found that spironolactone made up 47% of all oral medications prescribed to women for acne in 2023, up from 27% in 2017. Prescriptions for oral ...

  6. Comparison of bicalutamide with other antiandrogens - Wikipedia

    en.wikipedia.org/wiki/Comparison_of_bicalutamide...

    Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...

  7. Potassium-sparing diuretic - Wikipedia

    en.wikipedia.org/wiki/Potassium-sparing_diuretic

    Potassium-sparing diuretic

  8. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    The choice between the drugs is to a large degree determined by the characteristics of the patient being prescribed for, the drugs' side effects, and cost. Most drugs have other uses; sometimes the presence of other symptoms can warrant the use of one particular antihypertensive. Examples include: Age can affect the choice of medications.

  9. Canrenone - Wikipedia

    en.wikipedia.org/wiki/Canrenone

    Canrenone is an active metabolite of spironolactone, canrenoic acid, and potassium canrenoate, and is considered to be partially responsible for their effects. [9] It has been found to have approximately 10 to 25% of the potassium-sparing diuretic effect of spironolactone, [ 16 ] whereas another metabolite, 7α-thiomethylspironolactone (7α-TMS ...

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