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In histology (microscopic anatomy), the lobules of liver, or hepatic lobules, are small divisions of the liver defined at the microscopic scale. The hepatic lobule is a building block of the liver tissue , consisting of portal triads, hepatocytes arranged in linear cords between a capillary network, and a central vein .
A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein synthesis; Protein storage; Transformation of carbohydrates; Synthesis of cholesterol, bile salts and phospholipids; Detoxification, modification, and excretion of exogenous and endogenous substances
The liver parenchyma is the functional tissue of the organ made up of around 80% of the liver volume as hepatocytes. The other main type of liver cells are non-parenchymal. Non-parenchymal cells constitute 40% of the total number of liver cells but only 6.5% of its volume. [11]
Liver cytology is the branch of cytology that studies the liver cells and its functions. The liver is a vital organ, in charge of almost all the body’s metabolism. Main liver cells are hepatocytes, Kupffer cells, and hepatic stellate cells; each one with a specific function.
The liver is a vital organ and supports almost every other organ in the body. Because of its strategic location and multidimensional functions, the liver is prone to many diseases. [ 58 ] The bare area of the liver is a site that is vulnerable to the passing of infection from the abdominal cavity to the thoracic cavity .
Intralobular bile ducts (cholangioles or Canals of Hering) - simple cuboidal epithelium, then by hepatocytes; Bile canaliculi - two half-canaliculi formed by the hepatocytes facing the perisinusoidal space; Abdominal ultrasonography (with Doppler) of dilated intrahepatic bile ducts, in this case because of pancreatic cancer. The bile ducts are ...
The necessity of such a system is demonstrated by what happens when the system breaks down, as seen when advanced hepatic fibrosis in cirrhosis leads to hepatic encephalopathy in the brain owing to the blood being loaded with ammonia and other substances not conducive to brain function. Blood flow to the liver is unique in that it receives both ...
The LSECs contain 45% and 17% of the liver's total mass of pinocytic vesicles and lysosomes, and contain twice as many clathrin-coated pits per membrane unit, compared with two other major liver cells, Kupffer cells and hepatocytes, [5] reflecting the high capacity clathrin-mediated endocytic activity of LSECs.