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The National Drug and Alcohol Research Centre (NDARC) is an Australian research institution focusing on treatment and intervention in drug and alcohol abuse. Located at the University of New South Wales Randwick campus, in the suburbs of Sydney , NDARC was established in May, 1986, and officially opened in November, 1987.
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).
The Australian Institute of Health and Welfare states that 80% of Australians regularly consume alcohol. [1] In Australia, a third of the population live in remote and rural areas, where a proportion of these adults engage in risk-taking behaviours such as excessive alcohol misuse which is significantly higher than in major cities of Australia. [1]
[28] [29] Rather than substituting for alcohol, these drugs are intended to affect the desire to drink, either by directly reducing cravings as with acamprosate and topiramate, or by producing unpleasant effects when alcohol is consumed, as with disulfiram. These drugs can be effective if treatment is maintained, but compliance can be an issue ...
Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
A broad range of negative effects come with excessive alcohol consumption. Some of these include an increase in road and other accidents, crime, public and domestic violence, brain damage, liver disease, and the breakdown of social networks. [27] Alcohol related police detentions account for approximately 39% of all crimes. [24]
The Western Australian Alcohol and Drug Authority is a Western Australian authority that commenced operation on 1 January 1974.. The Authority was established under the Western Australian Alcohol and Drug Authority Act of 1974 [1] for the treatment, management, care and rehabilitation of people suffering from alcohol and drug abuse in Western Australia.
Drug and Alcohol Review is a peer-reviewed medical journal covering research related to alcohol and drug-related problems. It is the official journal of the Australasian Professional Society on Alcohol and other Drugs. It publishes seven issues annually. The journal is published by Wiley and the editor-in-chief is Robin Room (La Trobe University).