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Gout (/ ɡ aʊ t / GOWT [7]) is a form of inflammatory arthritis characterized by recurrent attacks of pain in a red, tender, hot, and swollen joint, [2] [8] caused by the deposition of needle-like crystals of uric acid known as monosodium urate crystals. [9]
Legg–Calvé–Perthes disease; Legius syndrome; Leiner's disease; Lelis syndrome; Lemierre's syndrome; Lennox–Gastaut syndrome; Lenz microphthalmia syndrome; Lenz–Majewski syndrome; Leriche's syndrome; Leschke syndrome; Lesch–Nyhan syndrome; Lethal congenital contracture syndrome; Lethal white syndrome
Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1] The knee joint is most commonly affected. [2]
Any part of the foot can be affected by diseases, with symptoms ranging from mild aches to more serious pain hindering one's ability to walk or bear weight. Most minor cases of foot pain can be responded to by home care treatments. However, when severe pain is present, medical attention is required as it is a disabling condition.
Drug eruptions are adverse drug reactions that present with cutaneous manifestations. [58] [59] [60] Acrodynia (calomel disease, erythredemic polyneuropathy, pink disease) Acute generalized exanthematous pustulosis (pustular drug eruption, toxic pustuloderma) Acute generalized exanthematous pustulosis; Adverse reaction to biologic agents
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), popularly known as baboon syndrome because of its resemblance to the distinctive red buttocks displayed by female baboons, is a systemic dermatitis characterized by well-demarcated patches of erythema distributed symmetrically on the buttocks. [1]
It most commonly affects women aged 13–35 years, approximately puberty through their prime. Some reports show affected women to men at 9:1. Rare cases have been shown to affect post-menopausal women, children, and men. Incident report is currently unknown. Although rare, men and children have been shown to be affected.
Several drug combinations with immunomodulators have been tested, for example, a combination of pentoxifylline (inhibitor of TNF-α) and a pentavalent antimonial at a high dose for 30 days in a small-scale (23 patients) randomised placebo-controlled study from Brazil achieved cure rates of 90% and reduced time to cure, [13] a result that should ...