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Amfepramone, also known as diethylpropion, is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant. [8] [9] It is used in the short-term management of obesity, along with dietary and lifestyle changes. [8]
They worked primarily by suppressing appetite, and had other beneficial effects such as increased alertness. Use of amphetamines increased over the subsequent decades, including Obetrol and culminating in the "rainbow diet pill" regime. [38] This was a combination of multiple pills, all thought to help with weight loss, taken throughout the day.
Phentermine is a stimulant and appetite suppressant. [3] Topiramate is an anticonvulsant that has weight loss side effects. [ 3 ] The exact mechanism of action for both drugs is unknown.
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Individually, naltrexone and bupropion each target pathways in the central nervous system that influence appetite and energy use. Bupropion is a reuptake inhibitor of both norepinephrine and dopamine , and a nicotinic acetylcholine receptor antagonist , and it activates proopiomelanocortin (POMC) neurons in the hypothalamus which give an effect ...
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