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Although the BioMart software is primarily used by the biomedical research community, it is designed in such a way that any type of data can be incorporated into the BioMart framework. The BioMart project originated at the European Bioinformatics Institute as a data management solution [1] for the Human Genome Project. [2]
The concept of human-equivalent energy (H-e) assists in understanding of energy flows in physical and biological systems by expressing energy units in human terms: it provides a “feel” for the use of a given amount of energy by expressing it in terms of the relative quantity of energy needed for human metabolism, [4] assuming an average human energy expenditure of 12,500 kJ per day and a ...
The solution of the equations, by either analytical or numerical means, describes how the biological system behaves either over time or at equilibrium. There are many different types of equations and the type of behavior that can occur is dependent on both the model and the equations used. The model often makes assumptions about the system.
For two-dimensional, plane strain problems the strain-displacement relations are = ; = [+] ; = Repeated differentiation of these relations, in order to remove the displacements and , gives us the two-dimensional compatibility condition for strains
A mouse-human hybrid is a genetically modified mouse whose genome has both mouse and human genes, thus being a murine form of a human-animal hybrid. For example, genetically modified mice may be born with human leukocyte antigen genes in order to provide a more realistic environment when introducing human white blood cells into them in order to ...
Modelling biological systems is a significant task of systems biology and mathematical biology. [ a ] Computational systems biology [ b ] [ 1 ] aims to develop and use efficient algorithms , data structures , visualization and communication tools with the goal of computer modelling of biological systems.
The two views are largely equivalent. In either case, for this particular architecture, the components of individual layers are independent of each other (e.g., the components of are independent of each other given their input ). This naturally enables a degree of parallelism in the implementation.
The model equations follow the principles of mass transport, fluid dynamics, and biochemistry in order to simulate the fate of a substance in the body. [9] Compartments are usually defined by grouping organs or tissues with similar blood perfusion rate and lipid content (i.e. organs for which chemicals' concentration vs. time profiles will be similar).