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The second edition appeared in 1986, with total content filling more than 2400 pages spread over three separate volumes. Although it was criticized for lack of cross-referencing and noticeable differences in writing styles due to a higher number of contributors, Miller's Anesthesia soon became the "standard encyclopedic textbook of anesthesia". [1]
Miller's Anesthesia [2] notes that a point mutation in the gene for human serum cholinesterase has been identified that changes Asp-70 to Gly in the atypical form of serum cholinesterase. The mutation in nucleotide 209, which changes codon 70 from GAT to GGT, was found by sequencing a genomic clone and sequencing selected regions of DNA ...
Download QR code; Print/export Download as PDF; Printable version; In other projects Wikimedia Commons; ... Membrane-mediated anesthesia; Miller's Anesthesia;
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Neuromuscular monitoring is recommended when neuromuscular-blocking drugs have been part of the general anesthesia and the doctor wishes to avoid postoperative residual curarization (PORC) in the patient, that is, the residual paralysis of muscles stemming from these drugs.
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
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