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[1] The second edition appeared in 1986, with total content filling more than 2400 pages spread over three separate volumes. Although it was criticized for lack of cross-referencing and noticeable differences in writing styles due to a higher number of contributors, Miller's Anesthesia soon became the "standard encyclopedic textbook of ...
Edward D. Miller Jr. (born 1943) is an American medical executive. He was the Frances Watt Baker, M.D. and Lenox D. Baker Jr., M.D. Dean of the Medical Faculty at Johns Hopkins University and the Chief Executive Officer of Johns Hopkins Medicine from 1997 to 2012.
The Meyer-Overton correlation for anaesthetics. A nonspecific mechanism of general anaesthetic action was first proposed by Emil Harless and Ernst von Bibra in 1847. [9] They suggested that general anaesthetics may act by dissolving in the fatty fraction of brain cells and removing fatty constituents from them, thus changing activity of brain cells and inducing anaesthesia.
Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) stimulus. MAC is used to compare the strengths, or potency, of anaesthetic vapours. [1]
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In anaesthesia and advanced airway management, rapid sequence induction (RSI) – also referred to as rapid sequence intubation or as rapid sequence induction and intubation (RSII) or as crash induction [1] – is a special process for endotracheal intubation that is used where the patient is at a high risk of pulmonary aspiration.
Total intravenous anesthesia (TIVA) refers to the intravenous administration of anesthetic agents to induce a temporary loss of sensation or awareness. The first study of TIVA was done in 1872 using chloral hydrate , [ 1 ] and the common anesthetic agent propofol was licensed in 1986.
General anaesthesia (UK) or general anesthesia (US) is medically induced loss of consciousness that renders a patient unarousable even by painful stimuli. [5] It is achieved through medications, which can be injected or inhaled, often with an analgesic and neuromuscular blocking agent .
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