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Agouti-signaling protein is a protein that in humans is encoded by the ASIP gene. [5] [6] It is responsible for the distribution of melanin pigment in mammals.[7] [8] Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). [9]
An agouti dog, also called wolf sable. In dogs, the agouti gene is associated with various coat colors and patterns. [10]The alleles at the A locus are related to the production of agouti-signaling protein (ASIP) and determine whether an animal expresses an agouti appearance and, by controlling the distribution of pigment in individual hairs, what type of agouti.
This is an accepted version of this page This is the latest accepted revision, reviewed on 28 January 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
Skin colors according to von Luschan's chromatic scale. Von Luschan's chromatic scale (VLS) is a method of classifying skin color. It is also called the von Luschan scale or von Luschan's scale. It is named after its inventor, Felix von Luschan. The equipment consisted of 36 opaque glass tiles which were compared to the subject's skin, ideally ...
The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin.
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Identifying human races in terms of skin colour, at least as one among several physiological characteristics, has been common since antiquity.Such divisions appeared in early modern scholarship, usually dividing humankind into four or five categories, with colour-based labels: red, yellow, black, white, and sometimes brown.
Richard Sturm and David Duffy describe 11 genes that affect skin pigmentation and explain most variations in human skin color, the most significant of which are MC1R, ASIP, OCA2, and TYR. [46] There is evidence that as many as 16 different genes could be responsible for eye color in humans; however, the main two genes associated with eye color ...