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  2. Gene expression profiling - Wikipedia

    en.wikipedia.org/wiki/Gene_expression_profiling

    In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment.

  3. Expression profiling - Wikipedia

    en.wikipedia.org/?title=Expression_profiling&...

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  4. Gene expression profiling in cancer - Wikipedia

    en.wikipedia.org/wiki/Gene_expression_profiling...

    Gene expression profiling is a technique used in molecular biology to query the expression of thousands of genes simultaneously. While almost all cells in an organism contain the entire genome of the organism, only a small subset of those genes is expressed as messenger RNA (mRNA) at any given time, and their relative expression can be evaluated.

  5. DNA microarray - Wikipedia

    en.wikipedia.org/wiki/DNA_microarray

    Due to the biological complexity of gene expression, the considerations of experimental design that are discussed in the expression profiling article are of critical importance if statistically and biologically valid conclusions are to be drawn from the data. There are three main elements to consider when designing a microarray experiment.

  6. Serial analysis of gene expression - Wikipedia

    en.wikipedia.org/wiki/Serial_analysis_of_gene...

    In the mid 2010s several techniques combined with Next Generation Sequencing were developed that employ the "tag" principle for "digital gene expression profiling" but without the use of the tagging enzyme. The "MACE" approach, (=Massive Analysis of cDNA Ends) generates tags somewhere in the last 1500 bps of a transcript.

  7. GeneCalling - Wikipedia

    en.wikipedia.org/wiki/GeneCalling

    The GeneCalling protocol measures levels of cDNA, which are correlated with gene expression levels of specific transcripts. Differences between gene expression in healthy tissues and disease or drug responsive tissues are examined and compared in this technology. [2] The technique has been applied to the study of human tissues [3] and plant ...

  8. Microarray analysis techniques - Wikipedia

    en.wikipedia.org/wiki/Microarray_analysis_techniques

    Example of an approximately 40,000 probe spotted oligo microarray with enlarged inset to show detail. Microarray analysis techniques are used in interpreting the data generated from experiments on DNA (Gene chip analysis), RNA, and protein microarrays, which allow researchers to investigate the expression state of a large number of genes – in many cases, an organism's entire genome – in a ...

  9. snRNA-seq - Wikipedia

    en.wikipedia.org/wiki/SnRNA-seq

    snRNA-seq, also known as single nucleus RNA sequencing, single nuclei RNA sequencing or sNuc-seq, is an RNA sequencing method for profiling gene expression in cells which are difficult to isolate, such as those from tissues that are archived or which are hard to be dissociated.