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Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]
BNP was first discovered in porcine brain tissue in 1988, which led to its initial naming as "brain natriuretic peptide", although subsequent research revealed that BNP is primarily produced and secreted by the ventricular myocardium (heart muscle) in response to increased ventricular blood volume and stretching.
Figure 1: The chemical structure of dichloroisoprenaline or dichloroisoproterenol (), abbreviated DCI — the first β-blocker to be developed. β adrenergic receptor antagonists (also called beta-blockers or β-blockers) were initially developed in the 1960s, for the treatment of angina pectoris but are now also used for hypertension, congestive heart failure and certain arrhythmias. [1]
In 1928, the term malignant hypertension was coined by physicians from the Mayo Clinic to describe a syndrome of very high blood pressure, severe retinopathy and inadequate kidney function which usually resulted in death within a year from strokes, heart failure or kidney failure. [12]
Werner Theodor Otto Forßmann (Forssmann in English; German pronunciation: [ˈvɛʁnɐ ˈfɔʁsˌman] ⓘ; 29 August 1904 – 1 June 1979) was a German researcher and physician from Germany who shared the 1956 Nobel Prize in Medicine (with Andre Frederic Cournand and Dickinson W. Richards) for developing a procedure that allowed cardiac catheterization.
There are five stages to the illness, the American Heart Association said in a new advisory This newly-discovered heart syndrome could be surprisingly common, experts say Skip to main content
By providing contact information, the Framingham Heart Study establishes a network of personal relationships, connecting participants through their relationships—friends, colleagues, relatives and neighbors. [20] Four risk factors for a precursor of heart failure are discovered. 30-year risk for serious cardiac events can be calculated.
A study of more than 36,000 people in the European Journal of Heart Failure found that median survival was reduced by more than a year among those who had both heart failure and Type 2 diabetes ...
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