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  2. Things You Probably Don't Know About Viagra (Like What It Was ...

    www.aol.com/things-probably-dont-know-viagra...

    Sildenafil can still be used to treat hypertension, but today, the primary use of this PDE5 inhibitor is to remedy ED. Other first-line treatment options for blood pressure and heart disease are ...

  3. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...

  4. What Does Viagra Actually Do to Your "Intimate" Experience? - AOL

    www.aol.com/does-viagra-actually-intimate...

    For example, a small study of 20 people that looked into Viagra’s effect on refractory time found that a standard 100mg dose of sildenafil citrate reduced the average male post-intimacy recovery ...

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra. It was approved by the Food and Drug Administration (FDA) in 1998 as the first oral medicine for erectile dysfunction. Later, in the year 2005, it was approved for the treatment of pulmonary arterial hypertension. [ 2 ]

  8. Daré Bioscience Announces Phase 3 Plans for Sildenafil Cream ...

    lite.aol.com/tech/story/0022/20241216/9319174.htm

    Sildenafil, a phosphodiesterase-5 (PDE-5) inhibitor, is the active ingredient in a tablet for oral administration currently marketed under the brand name Viagra ® for the treatment of ED in men. Sildenafil Cream, 3.6% (Sildenafil Cream) is an investigational, proprietary cream formulation of sildenafil designed for topical administration to ...

  9. Is Sildenafil Safe for This Common Male Problem? - AOL

    www.aol.com/sildenafil-safe-common-male-problem...

    Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.