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Acamprosate, sold under the brand name Campral, is a medication which reduces alcoholism cravings. [ 1 ] [ 5 ] It is thought to stabilize chemical signaling in the brain that would otherwise be disrupted by alcohol withdrawal . [ 6 ]
Acamprosate reduces the risk of relapse amongst alcohol-dependent persons. [163] [164] Acamprosate is not recommended in those with advanced, decompensated liver cirrhosis due to the risk of liver toxicity. [134] Naltrexone is a competitive antagonist for opioid receptors, effectively blocking the effects of endorphins and opioids.
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Currently, the FDA has approved three medications—naltrexone, acamprosate, and disulfiram—for the treatment of alcohol use disorder (AUD). However, there is insufficient data regarding the safety of these medications for pregnant women. [57] Naltrexone is a nonselective opioid antagonist that is used to treat AUD and opioid use disorder. [58]
Campral (acamprosate) for maintenance of abstinence from alcohol in patients with alcohol dependence; Celexa for depression (developed by Lundbeck) Cervidil (dinoprostone vaginal insert) for the initiation and/or continuation of cervical ripening in certain patients
The patient also experienced paranoid ideation (believing she was being poisoned and persecuted by co-employees), accompanied by sensory hallucinations. Symptoms developed after abrupt withdrawal of chlordiazepoxide and persisted for 14 months. Various psychiatric medications were trialed which were unsuccessful in alleviating the symptomatology.
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PILLS (Patient Information Language Localisation System) is a one-year effort by the European Commission to produce a prototype tool which will support the creation of various kinds of medical documentation simultaneously in multiple languages, by storing the information in a database and allowing a variety of forms and languages of output.