enow.com Web Search

Search results

1. Results from the WOW.Com Content Network

2. Pregabalin - Wikipedia

   en.wikipedia.org/wiki/Pregabalin

   Pregabalin is generally not regarded as efficacious in the treatment of acute pain. [55] In trials examining the utility of pregabalin for the treatment of acute post-surgical pain, no effect on overall pain levels was observed, but people did require less morphine and had fewer opioid-related side effects.

3. Gabapentinoid - Wikipedia

   en.wikipedia.org/wiki/Gabapentinoid

   [6] [12] Existing evidence on the use of gabapentinoids in chronic lower back pain is limited, and demonstrates significant risk of adverse effects, without any demonstrated benefit. [13] The main side-effects include: a feeling of sleepiness and tiredness, decreased blood pressure, nausea, vomiting and also glaucomatous visual hallucinations. [14]

4. Gabapentin - Wikipedia

   en.wikipedia.org/wiki/Gabapentin

   Sleepiness and dizziness are the most common side effects. Serious side effects include respiratory depression, and allergic reactions. [7] As with all other antiepileptic drugs approved by the FDA, gabapentin is labeled for an increased risk of suicide. Lower doses are recommended in those with kidney disease. [7]

5. Anticholinergic - Wikipedia

   en.wikipedia.org/wiki/Anticholinergic

   However, it is noted that opioid/antihistamine combinations are used clinically for their synergistic effect in the management of pain and maintenance of dissociative anesthesia (sedation) in such preparations as meperidine/promethazine (Mepergan) and dipipanone/cyclizine (Diconal), which act as strong anticholinergic agents.

6. Benzodiazepine withdrawal syndrome - Wikipedia

   en.wikipedia.org/wiki/Benzodiazepine_withdrawal...

   Improved reaction times were noted at 52 weeks in elderly patients free from benzodiazepines. This is an important function in the elderly, especially if they drive a car due to the increased risk of road traffic accidents in benzodiazepine users. [136] At the 24-week follow-up, 80% of people had successfully withdrawn from benzodiazepines.

7. Postherpetic neuralgia - Wikipedia

   en.wikipedia.org/wiki/Postherpetic_neuralgia

   Tricyclic antidepressants (TCAs), such as nortriptyline or desipramine, are effective in reducing postherpetic neuralgia pain but are limited by their numerous side effects. For every three people treated with a tricyclic antidepressant, one person is expected to have a clinically significant reduction in their pain (NNT=3). [ 2 ]

8. Mirogabalin - Wikipedia

   en.wikipedia.org/wiki/Mirogabalin

   Gabapentin and pregabalin are also members of this class. As a gabapentinoid, mirogabalin binds to the α 2 δ subunit of voltage-gated calcium channel (1 and 2), but with significantly higher potency than pregabalin. It has shown promising results in Phase II clinical trials for the treatment of diabetic peripheral neuropathic pain. [1] [2]

9. Vigabatrin - Wikipedia

   en.wikipedia.org/wiki/Vigabatrin

   Vigabatrin reduced cholecystokinin tetrapeptide-induced symptoms of panic disorder, in addition to elevated cortisol and ACTH levels, in healthy volunteers. [12]Vigabatrin is also used to treat seizures in succinic semialdehyde dehydrogenase deficiency (SSADHD), which is an inborn GABA metabolism defect that causes intellectual disability, hypotonia, seizures, speech disturbance, and ataxia ...