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The specific vitamins and minerals in AREDS-1 are vitamin C (500 mg), zinc (80 mg), vitamin E (400 IU), copper (2 mg) and beta-carotene (15 mg). In the AREDS-2 formulation, lutein (10 mg) and zeaxanthin (2 mg) replaced beta-carotene due to the risk of lung cancer in smokers taking beta-carotene. [ 2 ]
The macula (/ˈmakjʊlə/) [1] or macula lutea is an oval-shaped pigmented area in the center of the retina of the human eye and in other animals. The macula in humans has a diameter of around 5.5 mm (0.22 in) and is subdivided into the umbo, foveola, foveal avascular zone, fovea, parafovea, and perifovea areas.
Near-sighted vision (left), normal vision (right) A myopic individual can see clearly out to a certain distance (the far point of the eye), but objects placed beyond this distance appear blurred . [ 16 ] [ 25 ] If the extent of the myopia is great enough, even standard reading distances can be affected.
A person's visual acuity is registered documenting the following: whether the test was for distant or near vision, the eye(s) evaluated and whether corrective lenses (i.e. glasses or contact lenses) were used: Distance from the chart D (distant) for the evaluation done at 20 feet (6 m). N (near) for the evaluation done at 15.7 inches (400 mm).
[46] [needs update] Including lutein and zeaxanthin supplements in with a multivitamin does not improve progression of macular degeneration. [46] The need for high-quality studies looking at the safety of taking multivitamins has been highlighted. [46] According to the Harvard School of Public Health: "... many people don't eat the healthiest ...
In plants, the xanthophyll lutein is the most abundant carotenoid and its role in preventing age-related eye disease is currently under investigation. [5] Lutein and the other carotenoid pigments found in mature leaves are often not obvious because of the masking presence of chlorophyll. When chlorophyll is not present, as in autumn foliage ...
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