Search results
Results from the WOW.Com Content Network
P-type calcium channels were named after Purkinje cells, where they were initially encountered (Llinas et al. 1989), which are crucial in cerebellar function. Activation of the Purkinje cell by climbing fibers can shift its activity from a quiet state to a spontaneously active state and vice versa, serving as a kind of toggle switch. [25]
The Purkinje fibers are further specialized to rapidly conduct impulses (having numerous fast voltage-gated sodium channels and mitochondria, and fewer myofibrils, than the surrounding muscle tissue). Purkinje fibers take up stain differently from the surrounding muscle cells because of having relatively fewer myofibrils than other cardiac cells.
Early in development, Purkinje cells are innervated by multiple climbing fibers, but as the cerebellum matures, these inputs gradually become eliminated resulting in a single climbing fiber input per Purkinje cell. These fibers provide very powerful, excitatory input to the cerebellum which results in the generation of complex spike excitatory ...
Cerebellar granule cells form the thick granular layer of the cerebellar cortex and are among the smallest neurons in the brain. (The term granule cell is used for several unrelated types of small neurons in various parts of the brain.) Cerebellar granule cells are also the most numerous neurons in the brain: in humans, estimates of their total ...
Purkinje images are reflections of objects from the structure of the eye. They are also known as Purkinje reflexes and as Purkinje–Sanson images. At least four Purkinje images are usually visible in the normal eye. The first Purkinje image (P1) is the reflection from the outer surface of the cornea. The second Purkinje image (P2) is the ...
Purkinje fibers, located in the heart; The visual Purkinje effect of how human beings do not see color in dim light; Purkinje images, reflections of objects from the surface of the cornea, and from the anterior and posterior surfaces of the lens; Purkinje Incorporated, a company that develops healthcare information technology software and services
Plasticity of the synapse between a parallel fiber and a Purkinje cell is believed to be important for motor learning. [11] The function of cerebellar circuits is entirely dependent on processes carried out by the granular layer. Therefore, the function of granule cells determines the cerebellar function as a whole. [12]
The olivocerebellar tract, also known as olivocerebellar fibers, are neural fibers which originate at the olivary nucleus and pass out through the hilum and decussate with those from the opposite olive in the raphe nucleus, then as internal arcuate fibers they pass partly through and partly around the opposite olive and enter the inferior peduncle to be distributed to the cerebellar hemisphere ...