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2. Zinc L-carnosine - Wikipedia

   en.wikipedia.org/wiki/Zinc_L-carnosine

   Zinc L-carnosine (beta-alanyl-L-histidinato zinc [1]) (N-(3-aminopropionyl)-L-histidinato zinc [2]), often simply called zinc carnosine, and also known as polaprezinc, [3] is a mucosal protective [4] [5] chelate compound of zinc and L-carnosine invented by Hamari Chemicals, Ltd. [6] [7] It is a quadridentate 1:1 complex of a polymeric nature. [6]

3. Fexuprazan - Wikipedia

   en.wikipedia.org/wiki/Fexuprazan

   Fexuprazan (trade name Fexuclue) is a drug for the treatment of gastroesophageal reflux disease (GERD). [1] It is a potassium-competitive acid blocker. [2] Fexuprazan is approved for use in South Korea and Mexico. [3] [4]

4. Sucralfate - Wikipedia

   en.wikipedia.org/wiki/Sucralfate

   Sucralfate, sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. [3] [4] [5] Its usefulness in people infected by H. pylori is limited. [3]

5. Drugs for acid-related disorders - Wikipedia

   en.wikipedia.org/wiki/Drugs_for_acid-related...

   There are several classes of drugs for acid-related disorders, such as dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), or laryngopharyngeal reflux. The World Health Organization gives drugs in these classes the categorization code ATC code A02.

6. Proton-pump inhibitor - Wikipedia

   en.wikipedia.org/wiki/Proton-pump_inhibitor

   The proton pump is the terminal stage in gastric acid secretion, being directly responsible for secreting H + ions into the gastric lumen, making it an ideal target for inhibiting acid secretion. [ citation needed ] Because the H,K-ATPase is the final step of acid secretion, an inhibitor of this enzyme is more effective than receptor ...

7. Discovery and development of proton pump inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   Acid secretion by the human stomach results in a median diurnal pH of 1.4. This very large (>10 6 -fold) H + gradient is generated by the gastric H + /K + ATPase which is an ATP-driven proton pump. Hydrolysis of one ATP molecule is used to catalyse the electroneutral exchange of two luminal potassium ions for two cytoplasmic protons through the ...

8. Esophageal pH monitoring - Wikipedia

   en.wikipedia.org/wiki/Esophageal_pH_Monitoring

   In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.

9. Carnosine - Wikipedia

   en.wikipedia.org/wiki/Carnosine

   Carnosine (beta-alanyl-L-histidine) is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues. [citation needed] Carnosine was discovered by Russian chemist Vladimir Gulevich. [1] Carnosine is naturally produced by the body in the liver [2] from beta-alanine and histidine.