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PLINK [1] is a free, commonly used, open-source whole-genome association analysis toolset designed by Shaun Purcell.The software is designed flexibly to perform a wide range of basic, large-scale genetic analyses.
Schematic overview of the modular structure underlying procedures for gene set enrichment analysis. Gene set enrichment analysis (GSEA) (also called functional enrichment analysis or pathway enrichment analysis) is a method to identify classes of genes or proteins that are over-represented in a large set of genes or proteins, and may have an association with different phenotypes (e.g ...
Apriori [1] is an algorithm for frequent item set mining and association rule learning over relational databases.It proceeds by identifying the frequent individual items in the database and extending them to larger and larger item sets as long as those item sets appear sufficiently often in the database.
Regional association plot, showing individual SNPs in the LDL receptor region and their association to LDL-cholesterol levels. This type of plot is similar to the Manhattan plot in the lead section, but for a more limited section of the genome. The haploblock structure is visualized with colour scale and the association level is given by the ...
Kraken: [9] A set of tools for quality control and analysis of high-throughput sequence data. HTSeq [10] The Python script htseq-qa takes a file with sequencing reads (either raw or aligned reads) and produces a PDF file with useful plots to assess the technical quality of a run. mRIN [11] - Assessing mRNA integrity directly from RNA-Seq data.
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There are two important metrics for performing the association rules mining technique: support and confidence. Also, a priori algorithm is used to reduce the search space for the problem. [1] The support metric in the association rule learning algorithm is defined as the frequency of the antecedent or consequent appearing together in a data set ...
Average mortgage rates are edging down moderately week over week of Monday, January 6, 2024, though remain at elevated levels for benchmark 30-year and 15-year fixed terms, this despite three back ...