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Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [17] [18] Pregabalin also has antiallodynic properties.
Carpal tunnel syndrome is a neurological disorder that occurs when the median nerve, which runs from your forearm into the hand, becomes squeezed.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Carpal tunnel syndrome patients tend to have elevated carpal tunnel pressures (12-31mm Hg) compared to controls (2.5 - 13mm Hg). [ 23 ] [ 24 ] [ 25 ] Applying pressure to the carpal tunnel of normal subjects in a lab can produce mild neurophysiological changes at 30mm Hg with a rapid, complete sensory block at 60mm Hg. [ 26 ]
Carpal tunnel syndrome is a common nerve condition that happens when the median nerve — which runs from your forearm through your wrist into the palm of your hand — becomes pressed or squeezed ...
The antiepileptic medication pregabalin (Lyrica) was developed specifically for neuralgia and other neuropathic pain as a successor to gabapentin (Neurontin). [citation needed] High doses of anticonvulsant medicines—used to block nerve firing— and tricyclic antidepressants are generally effective in treating neuralgia.
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