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BamA is a β-barrel, outer membrane protein found in Gram-negative bacteria and it is the main and vital component of the β-barrel assembly machinery (BAM) complex in those bacteria. [1] BAM Complex consists of five components; BamB, BamC, BamD, BamE (all are lipoproteins ) and BamA (Outer membrane protein).
The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates the NF-κB transcription factor by masking the nuclear localization signals (NLS) of NF-κB proteins and keeping them sequestered in an inactive state in the cytoplasm.
18035 Ensembl ENSG00000100906 ENSMUSG00000021025 UniProt P25963 Q9Z1E3 RefSeq (mRNA) NM_020529 NM_010907 RefSeq (protein) NP_065390 NP_035037 Location (UCSC) Chr 14: 35.4 – 35.4 Mb Chr 12: 55.54 – 55.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse IκBα (n uclear f actor of k appa light polypeptide gene enhancer in B -cells i nhibitor a lpha; NFKBIA) is one member of a family ...
The dimerization partner, RB-like, E2F and multi-vulval class B (DREAM) complex is a protein complex responsible for the regulation of cell cycle-dependent gene expression. [ 1 ] [ 2 ] The complex is evolutionarily conserved, although some of its components vary from species to species.
Thus, several scaffolding molecules including IPS1/MAVS, TANK, AZI2/NAP1 or TBKBP1/SINTBAD (TANK-binding kinase 1-binding protein 1) can be recruited to the IKBKE-containing-complexes. Activated by polyubiquitination in response to TNFA and interleukin-1, regulates the NF-kappa-B signaling pathway through, at least, the phosphorylation of CYLD .
Burkholderia cepacia complex Scientific classification Domain: Bacteria Phylum: Pseudomonadota Class: Betaproteobacteria Order: Burkholderiales Family: Burkholderiaceae Genus: Burkholderia Species complex: B. cepacia complex Burkholderia cepacia complex (BCC) is a species complex consisting of Burkholderia cepacia and at least 20 different biochemically similar species of Gram-negative ...
Watch the Video. Click here to watch on YouTube. Many animals engage in elaborate mating rituals. For flight-ready birds, these often involve complex dance moves and peacock-like displays of grandeur.
The NLS is a sequence of basic amino acids that tags the protein as cargo destined for the nucleus. A cargo protein can contain either one or two of these motifs, which will bind to the major and/or minor binding sites on importin-α. [11] Overview of the nuclear protein import cycle.
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