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ChIP-on-chip (also known as ChIP-chip) is a technology that combines chromatin immunoprecipitation ('ChIP') with DNA microarray ("chip"). Like regular ChIP , ChIP-on-chip is used to investigate interactions between proteins and DNA in vivo .
Cell, a shorthand for Cell Broadband Engine Architecture, [a] is a 64-bit multi-core microprocessor and microarchitecture that combines a general-purpose PowerPC core of modest performance with streamlined coprocessing elements [2] which greatly accelerate multimedia and vector processing applications, as well as many other forms of dedicated computation.
Quick and quantitative ChIP (Q 2 ChIP): The assay uses 100,000 cells as starting material and is suitable for up to 1,000 histone ChIPs or 100 transcription factor ChIPs. Thus many chromatin samples can be prepared in parallel and stored, and Q 2 ChIP can be undertaken in a day.
The microelectrode array was an early demonstration of extensive surface functionalization of microelectrode arrays to support contractile muscle cells actively stimulated by spinal motor neurons with successful read out by dorsal root ganglion cells on the chip. [15]
3D Sarfus image of a DNA biochip. The microarray—the dense, two-dimensional grid of biosensors—is the critical component of a biochip platform. Typically, the sensors are deposited on a flat substrate, which may either be passive (e.g. silicon or glass) or active, the latter consisting of integrated electronics or micromechanical devices that perform or assist signal transduction.
7440/7450 micro-architecture family up to 1.5 GHz and 256 kB on-chip L2 cache and improved Altivec 7447/7457 micro-architecture family up to 1.83 GHz with 512 kB on-chip L2 cache 7448 micro-architecture family (2.0 GHz) in 90 nm with 1MB L2 cache and slightly improved AltiVec (out of order instructions).
In 2021, a team led by biophysicist Sangram Bagh realized a study with E. coli to solve 2 x 2 maze problems to probe the principle for distributed computing among cells. [ 10 ] [ 11 ] In 2024, FinalSpark, a Swiss biocomputing startup, launched an online platform enabling global researchers to conduct experiments remotely on biological neurons ...
ChIP-sequencing, also known as ChIP-seq, is a method used to analyze protein interactions with DNA. ChIP-seq combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to identify the binding sites of DNA-associated proteins. It can be used to map global binding sites precisely for any protein of interest.