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Amino acid replacement is a change from one amino acid to a different amino acid in a protein due to point mutation in the corresponding DNA sequence. It is caused by nonsynonymous missense mutation which changes the codon sequence to code other amino acid instead of the original.
For example, if the mutation occurs in the region of the gene responsible for coding, the amino acid sequence of the encoded protein may be altered, causing a change in the function, protein localization, stability of the protein or protein complex. Many methods have been proposed to predict the effects of missense mutations on proteins.
In cell biology, protein turnover refers to the replacement of older proteins as they are broken down within the cell. Different types of proteins have very different turnover rates. A balance between protein synthesis and protein degradation is required for good health and normal protein metabolism.
Fertility rates must level off to the replacement rate (the net reproduction rate should be 1). If the fertility rate remains higher than the replacement rate, the population would continue to grow. 2. Mortality rate must stop declining, that is, it must remain constant. 3. Lastly, the age structure must adjust to the new rates of fertility and ...
The gross reproduction rate (GRR) is the average number of daughters a woman would have if she survived all of her childbearing years, which is roughly to the age of 45, subject to the age-specific fertility rate and sex ratio at birth throughout that period. This rate is a measure of replacement fertility if mortality is not in the equation. [1]
If you've been having trouble with any of the connections or words in Saturday's puzzle, you're not alone and these hints should definitely help you out. Plus, I'll reveal the answers further down
In biology, a substitution model, also called models of sequence evolution, are Markov models that describe changes over evolutionary time. These models describe evolutionary changes in macromolecules, such as DNA sequences or protein sequences, that can be represented as sequence of symbols (e.g., A, C, G, and T in the case of DNA or the 20 "standard" proteinogenic amino acids in the case of ...
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