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Sulfasalazine metabolizes to sulfapyridine. Serum levels should be monitored every three months, and more frequently at the outset. Serum levels above 50 μg/L are associated with side effects. In rare cases, sulfasalazine can cause severe depression in young males. It can also cause oligospermia and temporary infertility.
Possible side effects of 5-ASA include, nausea and vomiting, reduced sperm count and damage to red or white blood cells, or to the liver, kidneys, pancreas, nerves or hearing. Allergic reactions to sulfasalazine characterized by dizziness, fever and skin rash have been reported in a small percentage of patients.
Combinations of DMARDs are often used, because each drug in the combination can be used in a smaller dose than if it were given alone, thus reducing the risk of side effects. [citation needed] Many patients receive an NSAID and at least one DMARD, sometimes with low-dose oral glucocorticoids. If disease remission is observed, regular NSAIDs or ...
“Chronic inflammation can affect the whole body, and in many cases displays no symptoms,” says Enright. Over time, it can be linked to many adverse health outcomes, including heart disease ...
Muscle cramps could also potentially stem from a nerve problem (such as nerve compression), exercising in the heat, a lack of stretching, muscle fatigue, body stress, medication side effects or ...
These NSAIDs, while reducing inflammation, also inhibit platelet aggregation and increase the risk of gastrointestinal ulcers and bleeds. [11] COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis, and some of these agents substantially increase the risk of heart attack.
Sulfasalazine; Mesalazine (5-Aminosalicylic acid) Side effects may include abdominal pain, diarrhea, headaches, and nausea. [1] References This page was last edited ...
2. Eat Smaller, More Frequent Meals. Instead of three main meals, try eating smaller, more frequent meals throughout the day. This can help if nausea is making it hard to feel like eating or if ...
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related to: how does sulfasalazine reduce inflammation side effects in the body- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261