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Frailty can have various symptoms including muscle weakness (reduced grip strength), slower walking speed, exhaustion, unintentional weight loss, and frequent falls. [ 3 ] [ 4 ] Older people with certain medical conditions such as diabetes , heart disease and dementia , are also more likely to have frailty.
Unwanted weight loss of more than 5% within 6 months. [2] [19] For people with a BMI of less than 20 kg/m 2, weight loss of more than 2%. [2] [19] [27] For people with sarcopenia, weight loss of more than 2%. [2] [19] [27] New ways to score and stage cachexia are being explored, particularly in people with advanced cancer. [19]
Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, [1] [2] [3] and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a ...
A few other major signs to look out for include extreme fatigue, headaches, fever, a butterfly-shaped rash across the cheeks and nose, hair loss, and Raynaud’s phenomenon (a condition in which ...
The signs and symptoms of Graves' disease generally result from the direct and indirect effects of hyperthyroidism, although they can also be caused by other thyroidal conditions, such as Graves' ophthalmopathy, goitre and pretibial myxedema. These clinical manifestations can involve virtually every system in the body.
Since exhaustion disorder results in a long-lasting and severe loss of function, usually brought on by work-related stress, time until "return to work" is considered the most important end-point when evaluating the effectiveness of various treatments. [58] The body of research is small, since the diagnosis is only recognized in a single country.
The most apparent sign of hypermetabolism is an abnormally high intake of calories followed by continuous weight loss. Internal symptoms of hypermetabolism include: peripheral insulin resistance, elevated catabolism of protein, carbohydrates and triglycerides, and a negative nitrogen balance in the body. [2]
A vitamin B12 deficiency — which, as mentioned, those with overweight or obesity are more at risk for — can lead to fatigue. And fatigue can make weight loss efforts like sticking to a healthy ...