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  2. Paneth cell - Wikipedia

    en.wikipedia.org/wiki/Paneth_cell

    Lysozyme is an antimicrobial enzyme that dissolves the cell walls of many bacteria, and phospholipase A2 is an enzyme specialized in the lysis of bacterial phospholipids. [10] This battery of secretory molecules gives Paneth cells a potent arsenal against a broad spectrum of agents, including bacteria, fungi and even some enveloped viruses .

  3. Intestinal gland - Wikipedia

    en.wikipedia.org/wiki/Intestinal_gland

    During each mitosis, one of the two daughter cells remains in the crypt as a stem cell, while the other differentiates and migrates up the side of the crypt and eventually into the villus. These stem cells can differentiate into either an absorptive (enterocytes) or secretory (Goblet cells, Paneth cells, enteroendocrine cells) lineages. [3]

  4. Intestinal epithelium - Wikipedia

    en.wikipedia.org/wiki/Intestinal_epithelium

    Enteroendocrine cells secrete various gastrointestinal hormones including secretin, pancreozymin, enteroglucagon among others. Subsets of sensory intestinal epithelial cells synapse with nerves, [9] and are known as neuropod cells. [10] Paneth cells produce antimicrobial peptides such as human alpha-defensin. [11] [12]

  5. Defensin - Wikipedia

    en.wikipedia.org/wiki/Defensin

    Defensin, alpha 5, Paneth cell-specific Defensin-5 DEFA6: Defensin, alpha 6, Paneth cell-specific Defensin-6 β-defensins: DEFB1: Defensin, beta 1 Beta-defensin 1 Are the most widely distributed, being secreted by leukocytes and epithelial cells of many kinds. For example, they can be found on the tongue, skin, cornea, salivary glands, kidneys ...

  6. Intestinal mucosal barrier - Wikipedia

    en.wikipedia.org/wiki/Intestinal_mucosal_barrier

    The intestinal mucosal barrier is a heterogeneous entity composed of physical, biochemical, and immune elements elaborated by the intestinal mucosa. The central component is the intestinal epithelial layer, which provides physical separation between the lumen and the body.

  7. Gastrointestinal wall - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_wall

    Absorptive cell: Epithelium/intestinal glands: Digestion and absorption of nutrients in chyme Goblet cell: Epithelium/intestinal glands: Secretion of mucus Paneth cell: Intestinal glands: Secretion of the bactericidal enzyme lysozyme; phagocytosis G cells: Intestinal glands of duodenum: Secretion of the hormone intestinal gastrin: I cells

  8. Alpha defensin - Wikipedia

    en.wikipedia.org/wiki/Alpha_defensin

    Alpha-defensins, which have been identified in humans, monkeys and several rodent species, are particularly abundant in neutrophils, certain macrophage populations and Paneth cells of the small intestine. Defensins are produced constitutively and/or in response to microbial products or proinflammatory cytokines.

  9. Gut-associated lymphoid tissue - Wikipedia

    en.wikipedia.org/wiki/Gut-associated_lymphoid_tissue

    The gut-associated lymphoid tissue lies throughout the intestine, covering an area of approximately 260–300 m 2. [5] In order to increase the surface area for absorption, the intestinal mucosa is made up of finger-like projections (), covered by a monolayer of epithelial cells, which separates the GALT from the lumen intestine and its contents.