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Paregoric was a household remedy in the 18th and 19th centuries when it was widely used to control diarrhea in adults and children, as an expectorant and cough medicine, to calm fretful children, and to rub on the gums to counteract the pain from teething. A formula for paregoric from Dr. Chase's Recipes (1865): [7]
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
Diphenoxylate/atropine, also known as co-phenotrope, is a combination of the medications diphenoxylate and atropine, used to treat diarrhea. [2] [3] It should not be used in those in whom Clostridioides difficile infection is a concern. [4] It is taken by mouth. [2] Onset is typically within an hour. [5]
Donnatal is a combination medication that ... whereas 55.5% reported mean improvement on treatment therapy. ... Further, they noted that among patients with diarrhea ...
A 2002 review showed that Lactobacillus reduced the average duration of acute diarrhea by 0.7 days and stool frequency by 1.6 on the second day of treatment. Dosage was most effective at more than ten billion colony-forming units of Lactobacillus during the first 48 hours of diarrhea. [ 9 ]
In 2020, the FDA announced the medication would require a Boxed Warning, its "most prominent warning," about the drug's "serious mental health side effects" and advised restricting its use to ...
Mild to moderate dehydration in children seen in an emergency department is best treated with ORT. Persons taking ORT should eat within six hours and return to their full diet within 24–48 hours. [9] Oral rehydration therapy may also be used as a treatment for the symptoms of dehydration and rehydration in burns in resource-limited settings. [10]