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In cellular biology, traction force microscopy (TFM) is an experimental method for determining the tractions on the surface of a cell by obtaining measurements of the surrounding displacement field within an in vitro extracellular matrix (ECM).
This is the source of traction required for migration; the focal adhesion acts as a molecular clutch when it tethers to the ECM and impedes the retrograde movement of actin, thus generating the pulling (traction) force at the site of the adhesion that is necessary for the cell to move forward.
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. [1] A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, and metabolism. Over the last decades of the 20th century, biochemistry has become successful at ...
An overview of the different components included in the field of chemical biology. Chemical biology is a scientific discipline between the fields of chemistry and biology.The discipline involves the application of chemical techniques, analysis, and often small molecules produced through synthetic chemistry, to the study and manipulation of biological systems. [1]
Mechanobiology is an emerging field of science at the interface of biology, engineering, chemistry and physics. It focuses on how physical forces and changes in the mechanical properties of cells and tissues contribute to development, cell differentiation, physiology, and disease.
Quantitatively, the stress is expressed by the Cauchy traction vector T defined as the traction force F between adjacent parts of the material across an imaginary separating surface S, divided by the area of S. [9]: 41–50 In a fluid at rest the force is perpendicular to the surface, and is the familiar pressure.
The field is broadly defined and includes foundations in biology, applied mathematics, statistics, biochemistry, chemistry, biophysics, molecular biology, genetics, genomics, computer science and evolution. Computational biology has become an important part of developing emerging technologies for the field of biology. [3]