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  2. Haemophilia A - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_A

    It occurs in males and in homozygous females (which is only possible in the daughters of a haemophilic male and a carrier or haemophiliac female [9]). However, mild haemophilia A is known to occur in heterozygous females due to X-inactivation , so it is recommended that levels of factor VIII and IX be measured in all known or potential carriers ...

  3. Haemophilia - Wikipedia

    en.wikipedia.org/wiki/Haemophilia

    Haemophilia (British English), or hemophilia (American English) [6] (from Ancient Greek αἷμα (haîma) 'blood' and φιλία (philía) 'love of'), [7] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.

  4. Haemophilia in European royalty - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_in_European...

    No living member of the present or past reigning dynasties of Europe is known to have symptoms of haemophilia or is believed to carry the gene for it. The last descendant of Victoria known to have the disease was Infante Gonzalo, born in 1914, although hundreds of descendants of Queen Victoria's (including males descended only through females ...

  5. Acquired haemophilia - Wikipedia

    en.wikipedia.org/wiki/Acquired_haemophilia

    Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII.These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding disorder.

  6. List of genetic disorders - Wikipedia

    en.wikipedia.org/wiki/List_of_genetic_disorders

    The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child.

  7. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    The cause for the disorder is related to a genetic mutation of the HBB gene. This gene is responsible for providing the instructions to produce beta-globin; one of the major components of hemoglobin. The two classification types of beta thalassemia are thalassemia major (also known as Cooley's anemia) and thalassemia intermedia.

  8. Factor VIII - Wikipedia

    en.wikipedia.org/wiki/Factor_VIII

    2157 14069 Ensembl ENSG00000185010 ENSMUSG00000031196 UniProt P00451 Q06194 RefSeq (mRNA) NM_000132 NM_019863 NM_001161373 NM_001161374 NM_007977 RefSeq (protein) NP_000123 NP_063916 NP_001154845 NP_001154846 NP_032003 Location (UCSC) Chr X: 154.84 – 155.03 Mb Chr X: 74.22 – 74.43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Coagulation factor VIII (Factor VIII, FVIII, also ...

  9. Contaminated haemophilia blood products - Wikipedia

    en.wikipedia.org/wiki/Contaminated_haemophilia...

    Contaminated hemophilia blood products were a serious public health problem in the late 1970s up to 1985. [citation needed] Hemophilia A causes a deficiency in Factor VIII, a protein required for blood clotting. Factor VIII injections are a common treatment to prevent or stop bleeding in people with hemophilia A. [1]

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