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Since the 2010s, oxybutynin has increasingly been used to treat hyperhidrosis (excessive sweating). [15] [16] Numerous studies have identified concrete benefits of the drug in treating this condition, but have not identified appropriate dosing or the full spectrum of possible side effects, although dry mouth is seemingly infrequent in patients with hyperhidrosis.
Anticholinergics used for hyperhidrosis include propantheline, glycopyrronium bromide or glycopyrrolate, oxybutynin, methantheline, and benzatropine. Use of these drugs can be limited, however, by side-effects, including dry mouth, urinary retention, constipation, and visual disturbances such as mydriasis and cycloplegia.
Drugs with muscarinic antagonist activity are widely used in medicine, in the treatment of low heart rate, overactive bladder, respiratory problems such as asthma and chronic obstructive pulmonary disease (COPD), and neurological problems such as Parkinson's disease and Alzheimer's disease.
Injected to paralyse muscles around face, hence reducing wrinkles (clinical or cosmetic uses) Reduce secretion Used in patients with hyperhidrosis and sialorrhoea; Headache prophylaxis Intramuscular or subcutaneous administration can reduce migraine frequency and severity [14] Beta-bungarotoxin / / Venom found in krait snakes; No clinical use ...
I just googled "hyperhidrosis oxybutynin" and there are over 6,300 results.... most of the start ones confirming the use of Oxybutynin for Hyperhidrosis. Also remember, drugs do not need to be licensed for a certain condition for it to be used for that condition, and that there are over 200 countries around the world, each one has a different ...
These are used for patients with over-active bladder muscles, who have lost the ability to hold their urine in. [2] Oxybutynin is a common anti-cholinergic medication used to reduce bladder contractions by blocking M3 muscarinic receptors in the detrusor muscle.
Glycopyrronium tosylate, sold under the brand name Qbrexza among others, is a medication used for the treatment of primary axillary hyperhidrosis. [ 1 ] [ 2 ] [ 3 ] It was approved for medical use in the United States in June 2018, [ 4 ] and in Japan in January 2022.
Glycopyrronium bromide affects the gastrointestinal tracts, liver and kidney but has a very limited effect on the brain and the central nervous system.In horse studies, after a single intravenous infusion, the observed tendencies of glycopyrronium followed a tri-exponential equation, by rapid disappearance from the blood followed by a prolonged terminal phase.
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